Polynucleotide Treatments

Regenerative polynucleotide and PDRN skin treatment in Cheltenham for hydration, texture, fine lines, dark circles and scarring.

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07813 609998

Polynucleotide treatments are hot news in skin care and aesthetics, and we are thrilled to bring them to the Cheltenham Skin & Facials clinic!

What are Polynucleotides?

Polynucleotides are chains of nucleotides, which are the building blocks of DNA. DNA is responsible for a huge host of bodily functions, including how skin develops. When we treat with polynucleotides, they help damaged DNA in skin cells repair, resulting in the cells functioning better.

This treatment stimulates fibroblast cells, which help form connective tissues like collagen and elastin – essential proteins that provide the skin with shape, volume and a youthful appearance.

These clever polynucleotide chains can also:

Reduce inflammation
Stabilise pigmentation
Improve the extracellular matrix of skin cells to boost hydration.
Plus, they have antioxidant activity, helping counteract and protect against factors like sun exposure and stress.
Essentially, they are a type of regenerative treatment that changes how DNA in your skin is expressed and encourages the body’s natural processes to produce healthier skin cells. By encouraging cell growth, cell turnover, improving elasticity, hydrating the skin and offering anti-inflammatory properties, this universal treatment can help address multiple skin concerns:
Dry, dehydrated skin
Dark circles
Rosacea
Acne scarring
Hyperpigmentation
Wrinkles, lines and sunken skin due to the ageing process

Treatment areas

This innovative treatment offers a host of possibilities throughout the body. Common treatments are focused around the upper, mid and lower face, including the under-eye area, but treatments can also be used in areas such as the following:

neck
face
hands
thighs
lips
décolletage (upper chest area)
inner arms
upper arms

PDRN next-generation skincare

PDRN is a next-generation, high-tech skincare ingredient celebrated for its ability to support skin recovery, reinforce the skin barrier, and improve overall skin quality.

Originally studied in wound-healing settings, it has become a sought-after addition to advanced, medical-inspired skincare for its restorative, skin-supportive benefits. PDRN is often used to help calm stressed-looking skin, boost hydration, refine texture, and soften the appearance of fine lines, making it especially appealing for clients seeking healthier-looking, stronger, more radiant skin over time.

Lumi Eyes

Brighten, smooth and refresh the under-eye area with Lumi Eyes polynucleotides delivered by Tixel — no injections and no downtime.

Lumi Eyes is a polynucleotide treatment for dark circles, fine lines and thin or crepey under-eye skin. It supports collagen production and skin repair, helping the eye area look smoother, brighter and better hydrated.

Unlike filler, Lumi Eyes does not add volume. It focuses on improving the quality and condition of the delicate skin around the eyes.

We deliver the treatment with tixel rather than needlys so much less side effects,

How do polynucleotides differ from other treatments?

Polynucleotides work at a deeper cellular level to repair DNA in skin cells and encourage the natural production of elastin and collagen. This makes the treatment different from other established treatments, such as Profhilo. The results from polynucleotides can take longer to show than those from other treatments, but this is coupled with increased longevity.

Side effects are minimal. Some people may experience mild bruising, small bumps or swelling at the injection site, but this is temporary and usually resolves shortly after the treatment. The treatment itself is less than 30 minutes (plus numbing time).

Best results are seen 3 months after the course of treatments, once collagen production is optimised. Single maintenance treatments are recommended every 3-5 months.

A course of 3 treatments is advised, spaced 2-4 weeks apart for optimum results. Polynucleotides deliver significant results on their own, but when combined with treatments such as tixel and/or skin boosters, the results are amplified, delivering next-level skin rejuvenation.

A consultation is required to discuss the best treatment plan for you.

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Reviews

Clients travel from across Cheltenham and the Cotswolds for honest advice, personalised care and results that last. Here are just a few of their words:

⭐⭐⭐⭐⭐

Sonia is absolutely amazing — so professional, knowledgeable, and genuinely passionate about skin health. The range of treatments she offers is fantastic. I had polynucleotides with microneedling, and the results have exceeded my expectations; my skin looks and feels incredible. I can’t recommend Cheltenham Skin and Facials highly enough and would definitely recommend it to friends.

Gill in Cheltenham

You can read many more 5‑star Google reviews from clients.

    
 
 
       Posted on Google  
   
   DiLun 
 
 
 
 Trustindex verifies that the original source of the review is Google. I had such an amazing experience having microneedling and Tixel around my eyes. From the moment I arrived, I felt so well looked after and completely at ease.
Everything was explained to me in detail, which made me feel really comfortable and confident about the treatment. Sonia is incredibly knowledgeable, professional and clearly passionate about what she does. I genuinely felt like I was in safe hands throughout the whole experience.
I couldn’t have asked for better care and attention. I’m so happy I chose this place and would highly recommend Sonia to anyone considering these treatments! ❤️
  
 
      Posted on Google  
   
   Carol Cowlishaw 
 
 
 
 Trustindex verifies that the original source of the review is Google. Very happy with sensible advice and treatment from Sonia
  
 
      Posted on Google  
   
   Annie.Browne 
 
 
 
 Trustindex verifies that the original source of the review is Google. I had the Intraceuticals Oxygen facial with Sonia this week. My skin is looking and feeling amazing. Having regular treatments with Sonia is really showing benefits, not only after the treatment but staying smooth and plump between treatments. Thank you so much, it is really making a difference.
  
 
      Posted on Google  
   
   Natalie Davis 
 
 
 
 Trustindex verifies that the original source of the review is Google. I had a wonderful hydrating facial with Sonia. She clearly has excellent knowledge on products and gave me advise on what to use at home in the most cost effective way. Easy parking, clean and elegant space and top knowledge. Highly recommend Sonia for your skincare/facial needs.
  
 
      Posted on Google  
   
   Gail Pole 
 
 
 
 Trustindex verifies that the original source of the review is Google. Sonia always delivers a first class service , examining your skin and explaining fully how she can help with your requirements. I have seen a definite improvement in the texture and fullness of my skin , looking fresher and receiving many compliments on it . Sonia is highly professional and extremely knowledgeable in her field. I always feel comfortable talking about my skin and undergoing any treatments . It is well worth a visit or many .
  
 
      Posted on Google  
   
   Natasha Boyd 
 
 
 
 Trustindex verifies that the original source of the review is Google. I came to Sonia who was recommended by my dermatologist for IPL laser treatment. Im over the moon with the results. Shes very warm and welcoming, and so knowledgeable. Would highly recommend!!!
  
 
      Posted on Google  
   
   Margaret Gray 
 
 
 
 Trustindex verifies that the original source of the review is Google. My first visit was slightly helpfull, and I think it would have been more beneficial if I hadn't been on a pain blocking medication.
I will certainly return after I have seen the surgeon & pharmacist
  
 
      Posted on Google  
   
   Linda Castle 
 
 
 
 Trustindex verifies that the original source of the review is Google. I had Tixel eye treatment for heavy eye lids and bags under the eyes.  Thought I would try it, to avoid eye surgery.  It stings a little bit but well worth it. Sonia is very knowledgeable and explained everything in a relaxed setting.  I would definitely recommend her.
  
 
      Posted on Google  
   
   Jack Cleverley 
 
 
 
 Trustindex verifies that the original source of the review is Google. I had Tixel Treatment for acne scarring on my back and face and I'm really happy with the results.  If you're looking into having Tixel Treatment I would highly recommend Sonia.
  
 
      Posted on Google  
   
   Beverley Strait 
 
 
 
 Trustindex verifies that the original source of the review is Google. My first visit with Sonia,was really relaxing and Sonia expert knowledge,recommend the facial I needed.my skin felt fabulous after.i would highly recommend
It’s now my third visit with Sonia ,Sonia is so knowledgeable and makes you feel so comfortable,my skin feels better than it ever has ,thank you ,I will be back very soon .Bev .x

Visit our Cheltenham skin clinic.

Visits to Cheltenham Skin & Facials by Sonia Norman are by appointment only, so please book your skincare consultation or treatment before attending the clinic. To help us keep your treatment experience calm and relaxing, please aim to arrive around 5 minutes before your appointment time. Our waiting area is quite small, and arriving much earlier may disrupt treatments already in progress. Thank you for your understanding.

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Our clinic is just 2 minutes from Cheltenham town centre, with free 4-hour on-street parking or on the gravel driveway.